by perchlorate | Sep 1, 2022 | Science
In risk assessment, the “point of departure” is the dose selected as the starting point to which uncertainty or safety factors are applied to derive a “safe” dose. See the EPA’s definition of “point of departure” on their website »...
by perchlorate | Sep 1, 2022 | Science
By definition, an RfD assumes exposure over a lifetime and takes into account special considerations of sensitive populations such as pregnant women, children, infants and fetuses. Read the U.S. EPA’s definition of a reference dose on their website » The NAS Committee...
by perchlorate | Sep 1, 2022 | Science
The NAS Committee made several recommendations for future research, noting that sufficient data now exists to move forward with the regulatory process. Since the NAS report, multiple studies have filled the few data gaps identified by NAS and have confirmed the NAS...
by perchlorate | Sep 1, 2022 | Science
EPA uses standard default conversion factors for body weight (70 kilograms) and tap water consumption (2 liters per day) to translate RfDs to drinking water equivalents in ppb. For most people in a population, these assumptions are conservative as most people do not...
by perchlorate | Sep 1, 2022 | Science
In 2007, the State of California —accounting for perchlorate exposure from water, farm products and cow’s milk — enacted a Maximum Contaminant Level (MCL) for perchlorate in drinking water of 6 ppb. This is an exceptionally conservative approach considering...
by perchlorate | Sep 1, 2022 | Science
California’s current MCL is “final” in that it is currently enforceable, but is under review by regulatory authorities as part of a review process required by state law. At the federal level, the U.S. EPA has decided to set a national drinking water...
