by perchlorate | Sep 1, 2022 | Science
The NAS Committee defines a NOEL as “the highest dose at which there are no statistically or biologically significant increases in the frequency or severity of any effect between the exposed populations and its appropriate control.” on page 168 of the...
by perchlorate | Sep 1, 2022 | Science
As with most issues in life, health and safety, decisions must be made absent absolute certainty. “Uncertainty” or “safety” factors account for a lack of scientific data or to address possible variability in population sensitivity when deriving...
by perchlorate | Sep 1, 2022 | Science
Applying a safety factor to a NOEL is unusual and no precedent has been identified. The NAS Committee acknowledges its recommendation “differs from the traditional approach.” (See page 15) Moreover, the NAS Committee does not provide supporting precedent...
